Caffeine augments the prothrombotic but not the fibrolynic response to exercise

Development of clots pose a risk of cardiovascular and cerebrovascular accidents. Prothrombotic (clotting events) and fibrolynic (clot dissolving) can be influenced by altitude (thicker more viscous blood), inactivity (plane flights), genetics (haemochromatosis, prothrombin factor and/or Leyden's factor V), and paradoxically caffeine ingestion around exercise.

Investigators studied the affect of a single dose of caffeine during a single acute high intensity. They found the fibrolynic effects of exercise were not affected by caffeine. However, caffeine did increase coagulation factor VIII, which suggests an elevated risk of clotting (Nagelkirk et al 2019, Med Sc Sp Ex, 51, 3, 421-425).

4 April 2019

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Updated : 15/03/2018